Ground substance

Nitazenes are a powerful class of street drugs emerging across the US

Retrieved on:

Giovedì, Febbraio 15, 2024

Researchers have relatively little information on how the human body reacts to nitazenes because the drugs have never gone through clinical trials.

Key Points:

Researchers have relatively little information on how the human body reacts to nitazenes because the drugs have never gone through clinical trials.
As law enforcement has cracked down on other drugs such as fentanyl, illegal labs have used historical pharmacology research to formulate analogs of nitazenes as street drugs.
Although nitazenes are now identified as illegal street drugs in numerous countries, many medical providers aren’t even aware they exist.
Nitazenes are also mixed with other street drugs such as heroin and fentanyl and with fake oxycodone pills, without users knowing it.

'Premium Clean' expands its environmentally friendly business

Retrieved on:

Venerdì, Febbraio 9, 2024

Volatile organic compound, Skin, Transport, Organic compound, Ground substance, Risk, Detergent, Carpet cleaning, Environment, Allergy, Renewable energy

The increasing demand for specialised eco-friendly cleaning services meant the company quickly expanded its operations to cater to the needs of the growing clientele.

Key Points:

The increasing demand for specialised eco-friendly cleaning services meant the company quickly expanded its operations to cater to the needs of the growing clientele.
Frequently, business owners and facility managers express a desire to transition towards more environmentally friendly cleaning practices, but they often question the efficiency of green products when compared to traditional ones due to lack of information.
Traditional cleaning products often release volatile organic compounds (VOCs), contributing to poor air quality.
In contrast, many eco-friendly cleaning products are produced using sustainable manufacturing techniques that rely on renewable energy sources.

Updates on Human Abuse Potential Studies: Challenges and Regulatory Guidelines, Upcoming Webinar Hosted by Xtalks

Retrieved on:

Giovedì, Febbraio 8, 2024

Collection, MD, FDA, Food, Ground substance, Documentation, Psychological abuse, Drug development, Hallucinogen, Doctor of Philosophy, Knowledge, Medical device

TORONTO, Feb. 8, 2024 /PRNewswire-PRWeb/ -- Participate in this crucial webinar delving into the latest insights from the Cross-Company Abuse Liability Council (CCALC) and The Food and Drug Administration (FDA) in drug development and clinical evaluation of human drug abuse and dependence potential. This webinar aims to discuss current knowledge and recent updates on the clinical evaluation of the abuse and dependence potential of drugs. In September 2023, the CCALC – a group of representatives from across the industry – held its first face-to-face meeting with members of the Controlled Substances Staff of The FDA since 2018. At this meeting, key opinion leaders discussed nonclinical and clinical assessments, current issues in the design and analysis of these studies and pertinent topics that have emerged based on recent trends in drug development (e.g., hallucinogens). The clinical portion of the meeting discussed a broad range of topics; however, the current webinar will focus on updating attendees on:

Key Points:

In this free webinar, gain insights into key topics on the clinical evaluation of abuse and dependence potential discussed at the September 2023 CCALC meeting.
Attendees will learn about recent recommendations on the design and analysis of human abuse potential studies.
Attendees will also receive an update on best practices for the collection and documentation of abuse-related adverse events.
This webinar aims to discuss current knowledge and recent updates on the clinical evaluation of the abuse and dependence potential of drugs.

Mothers Against Drunk Driving® (MADD) and Diageo North America Kick Off Partnership to Tackle Impaired Driving in the U.S.

Retrieved on:

Giovedì, Febbraio 8, 2024

WASHINGTON, Feb. 8, 2024 /PRNewswire-PRWeb/ -- Mothers Against Drunk Driving® (MADD) and Diageo North America have agreed to a new partnership to collaborate on public awareness and education campaigns aimed at ending drunk driving.

Key Points:

WASHINGTON, Feb. 8, 2024 /PRNewswire-PRWeb/ -- Mothers Against Drunk Driving® (MADD) and Diageo North America have agreed to a new partnership to collaborate on public awareness and education campaigns aimed at ending drunk driving.
Diageo, which has a proven track record of effective programming to prevent impaired driving, is an inaugural member in the launch of the MADD Network.
Diageo has a record of implementing and supporting multi-agency drunk driving programs that address education and enforcement all over the world.
MADD and Diageo North America will announce additional details about their partnership in the near future.

Mothers Against Drunk Driving® (MADD) and Diageo North America Kick Off Partnership to Tackle Impaired Driving in the U.S.

Retrieved on:

Giovedì, Febbraio 8, 2024

Mothers Against Drunk Driving® (MADD) and Diageo North America have agreed to a new partnership to collaborate on public awareness and education campaigns aimed at ending drunk driving.

Key Points:

Mothers Against Drunk Driving® (MADD) and Diageo North America have agreed to a new partnership to collaborate on public awareness and education campaigns aimed at ending drunk driving.
Diageo, which has a proven track record of effective programming to prevent impaired driving, is an inaugural member in the launch of the MADD Network.
“In recent years we have witnessed a surge in drunk driving.
Supporting the enforcement of drunk driving highly visible laws where they exist and the establishment of effective laws where they don’t.

Laser Photonics’ CleanTech Laser Cleaning System Streamlines Brewery Operations

Retrieved on:

Giovedì, Febbraio 8, 2024

Laser Photonics Corporation (LPC), a leading global developer of CleanTech laser systems for laser cleaning and other material applications, highlights a key set of applications for its industrial laser cleaning systems in the beer brewing industry.

Key Points:

Laser Photonics Corporation (LPC), a leading global developer of CleanTech laser systems for laser cleaning and other material applications, highlights a key set of applications for its industrial laser cleaning systems in the beer brewing industry.
CleanTech laser cleaning systems can effectively replace grit blasting or acid etching for cleaning applications, even if the contamination is deep.
Traditional caustic, chemical, or electrical cleaning procedures can lead to further functional problems or higher costs that are eliminated with the use of CleanTech laser cleaning systems.
Laser cleaning mitigates these concerns for the full range of metals used in a brewery, both inside and outside of pipes, pots, and other components.

RS Adds Three New Industrial Suppliers

Retrieved on:

Lunedì, Febbraio 5, 2024

FORT WORTH, Texas, Feb. 5, 2024 /PRNewswire/ -- RS, a trading brand of RS Group plc (LSE: RS1), a global provider of product and service solutions for industrial customers, recently added three new suppliers to its line card. The three new suppliers — Brennan, Fairview Microwave, and MENNEKES — provide RS customers with an even broader selection of electrical, electronic, and mechanical solutions engineered to deliver outstanding performance and value in applications extending throughout every segment of the industrial market.

Key Points:

The three new suppliers — Brennan, Fairview Microwave, and MENNEKES — provide RS customers with access to even more electrical, electronic, and mechanical products proven to deliver outstanding performance and value in virtually every segment of the industrial market.
FORT WORTH, Texas, Feb. 5, 2024 /PRNewswire/ -- RS , a trading brand of RS Group plc (LSE: RS1), a global provider of product and service solutions for industrial customers, recently added three new suppliers to its line card.
The three new suppliers — Brennan , Fairview Microwave , and MENNEKES — provide RS customers with an even broader selection of electrical, electronic, and mechanical solutions engineered to deliver outstanding performance and value in applications extending throughout every segment of the industrial market.
RS adds new products engineered to deliver outstanding performance and value in every segment of the industrial market.

Societal CDMO and Benuvia Sign Co-Marketing Agreement Designed to Promote Complementary CDMO and API Manufacturing Services to Drug Developers

Retrieved on:

Giovedì, Febbraio 1, 2024

CGMP, New Drug Application, CDMO, Society, API, DEA, Cannabinoid, Drug Enforcement Administration, Drug development, Ground substance, Schedule, Pharmaceutical industry

GAINESVILLE, Ga. and ROUND ROCK, Texas, Feb. 01, 2024 (GLOBE NEWSWIRE) -- Societal CDMO, Inc. (“Societal CDMO”; NASDAQ: SCTL), a contract development and manufacturing organization (CDMO) dedicated to solving complex formulation and manufacturing challenges primarily in small molecule therapeutic development, and Benuvia Operations, LLC, a U.S.-based drug developer and manufacturer of active pharmaceutical ingredients (APIs) with a specialized expertise in controlled substances (cannabinoids and psychedelics), today announced the signing of a co-marketing agreement. The agreement is designed to allow the companies to promote each other’s complementary contract development and manufacturing services to their respective customer bases and new business prospects. As part of the agreement, the companies will highlight Benuvia’s specific expertise as a manufacturer of drug substance (API) and Societal’s focus on manufacturing drug product. While the agreement is not limited to any specific therapeutic indication or modality, the companies will specifically focus on leveraging their unique expertise in the area of psychedelics to address this expanding drug development market.

Key Points:

The agreement is designed to allow the companies to promote each other’s complementary contract development and manufacturing services to their respective customer bases and new business prospects.
As part of the agreement, the companies will highlight Benuvia’s specific expertise as a manufacturer of drug substance (API) and Societal’s focus on manufacturing drug product.
Societal CDMO possesses a broad range of CDMO capabilities spanning formulation development, analytical testing and manufacturing of oral solid dose finished drug products.
Benuvia Operations, LLC, is an end-to-end CDMO with vertically integrated pharmaceutical services ranging from drug and formulation development, fully-integrated analytical services and manufacturing of oral liquid and aerosol solutions.

Optimi Health Secures Amendment to Increase Quantities Of MDMA, MDA, And 2C-B Under Controlled Drugs And Substances Dealer’s Licence

Retrieved on:

Venerdì, Gennaio 19, 2024

MDMA, DMF, Health, Part, Annual Review, Documentation, API, GMP, Communication, Food, Drug Master File, MDA, Health Canada, Ground substance, DEL, FRA

Effectively implemented on January 16, 2024, the amendment allows substantial increases in the quantities of MDMA, MDA, and 2CB under subsection J.01.059(4) of Part J of the Food and Drug Regulations.

Key Points:

Effectively implemented on January 16, 2024, the amendment allows substantial increases in the quantities of MDMA, MDA, and 2CB under subsection J.01.059(4) of Part J of the Food and Drug Regulations.
Terms of the amendment now permit the following increases:
N-METHYL-3,4-METHYLENEDIOXY AMPHETAMINE (MDMA) – from 2kg to 20kg.
It enhances our competitive advantage and perfectly aligns with our vision to be the leading global supplier of GMP MDMA and other psychedelic substances."
Optimi now has Health Canada approval to manufacture the following controlled substances:

Adani Has Emerged Stronger, Says Gautam Adani in a Statement, a Year Post Short-seller's Attack

Retrieved on:

Giovedì, Gennaio 25, 2024

The following is a statement provided by Adani Group Chairman Gautam Adani:

Key Points:

The following is a statement provided by Adani Group Chairman Gautam Adani:
This press release features multimedia.
This, however, was a unique two-dimensional attack – a financial one, of course, and also one that played out into the political space – each feeding off the other.
The trials and tribulations of the past year have taught us valuable lessons, made us stronger and reaffirmed our faith in Indian institutions.
I believe we have emerged even stronger from this experience and even more unwavering in our resolve to continue our humble contribution to the India growth story.