Dry eye syndrome

Wize Pharma Announces Presentation of New Data on LO2A in the Treatment of Dry Eye Syndrome in Patients with Sjögren's Syndrome

Retrieved on: 
Martedì, Maggio 22, 2018
RTT, Anatomy, Medicine, Autoimmune diseases, Animal health, Dry eye syndrome, Sjögren syndrome

The poster presentation titled, "The anti-inflammatory effect of isotonic glycerol in Sjgren's syndrome-related dry eye" was delivered by Dr. Huba J.

Key Points: 
  • The poster presentation titled, "The anti-inflammatory effect of isotonic glycerol in Sjgren's syndrome-related dry eye" was delivered by Dr. Huba J.
  • "Based on this study, data shows that using LO2A resulted in a significant improvement of the subjective and objective symptoms of the Sjgren's syndrome-related dry eye disease.
  • This data supports our development efforts for LO2A in multiple markets including Israel where we are currently enrolling patients in a randomized, double-masked Phase IV study in this indication.
  • Wize is currently conducting a Phase II trial of LO2A for patients with CCH and a Phase IV study of LO2A for patients with Sjgren's.

Alcon teams up with Venus Williams, tennis champion and dry eye sufferer, to launch Systane® Complete eye drops

Retrieved on: 
Giovedì, Maggio 17, 2018
Ophthalmology, Health, Medicine, RTT, Dry eye syndrome, Eye drop

Systane Complete, a new formula designed to provide relief for every major type of dry eye, is an ideal first-line treatment option for people who suffer from evaporative dry eye, aqueous tear deficient dry eye or mixed dry eye.

Key Points: 
  • Systane Complete, a new formula designed to provide relief for every major type of dry eye, is an ideal first-line treatment option for people who suffer from evaporative dry eye, aqueous tear deficient dry eye or mixed dry eye.
  • In addition to welcoming Williams to the Systane family, Alcon will continue its collaboration with mountain climber Lisa Thompson as she moves from her existing dry eye treatment, Systane Ultra, to the new Systane Complete.
  • Systane Complete joins the full line of Systane lubricant eye drops, including Systane Ultra and Systane Balance.
  • Systane Complete is indicated as a first-line treatment option for people who suffer from evaporative dry eye, aqueous tear-deficient dry eye or mixed dry eye.

ReGenTree Presents Results of a Comparison Study of RGN-259 and Approved Prescription Drugs for Dry Eye Syndrome in a Mouse Model at ARVO

Retrieved on: 
Mercoledì, Maggio 2, 2018
Ophthalmology, RTT, Anatomy, Dry eye syndrome, Goblet cell, Cornea, Keratopathy

The study found that RGN-259 treatment promoted recovery of mucins and goblet cells, improved corneal integrity, increased tears, and reduced inflammation in a dry eye mouse model.

Key Points: 
  • The study found that RGN-259 treatment promoted recovery of mucins and goblet cells, improved corneal integrity, increased tears, and reduced inflammation in a dry eye mouse model.
  • RGN-259 has also demonstrated a strong safety profile with fewer side effects compared to approved products currently on the market.
  • Additionally, RGN-259 is being developed in patients with dry eye syndrome in Asia through RegeneRx's two Asian partnerships.
  • In addition to dry eye, the company is currently conducting a Phase 3 study for neurotrophic keratopathy (NK), an orphan indication in ophthalmology.

Aldeyra Therapeutics Presents Dry Eye Disease Phase 2a Clinical Trial Results at the Association for Research in Vision and Ophthalmology 2018 Annual Meeting

Retrieved on: 
Martedì, Maggio 1, 2018
Health, RTT, Clinical trial, Design of experiments, Drug discovery, Pharmaceutical industry, Product testing, Dry eye syndrome

The primary objective of the trial, to select a formulation for Phase 2b clinical testing, was achieved with the advancement of 0.1% reproxalap.

Key Points: 
  • The primary objective of the trial, to select a formulation for Phase 2b clinical testing, was achieved with the advancement of 0.1% reproxalap.
  • "Reproxalap could represent an important treatment for many patients that suffer from dry eye disease," commented Gary Foulks, M.D., F.A.C.S.
  • "The activity demonstrated within one week of therapy in the Phase 2a clinical trial presented today suggests that reproxalap could have significant potential for the treatment of dry eye disease."
  • In January 2018, Aldeyra announced the initiation of a Phase 2b clinical trial of topical ocular reproxalap in dry eye disease.

Sight Sciences Initiates U.S. Pivotal Trial of the TearCare® System for the Treatment of Dry Eye Disease

Retrieved on: 
Lunedì, Aprile 30, 2018
Ophthalmology, Vision, Health, RTT, Dry eye syndrome, Meibomian gland, Eye care professional, Rolando Toyos

"We need additional treatment options for dry eye," said Edward Holland, MD, Director of Cornea Services at Cincinnati Eye Institute and Professor of Ophthalmology at the University of Cincinnati.

Key Points: 
  • "We need additional treatment options for dry eye," said Edward Holland, MD, Director of Cornea Services at Cincinnati Eye Institute and Professor of Ophthalmology at the University of Cincinnati.
  • Meibomian gland dysfunction is the most common cause of dry eye disease.
  • "The initiation of this study is a significant milestone for Sight Sciences and our cutting-edge TearCare technology," said Paul Badawi, President and Chief Executive Officer of Sight Sciences.
  • Our pivotal trial brings us one step closer to our vision of delivering a first-class dry eye treatment experience for both patients and eye care professionals."

Global Dry Eye Epidemiology and Patient Flow Analysis 2018

Retrieved on: 
Giovedì, Aprile 19, 2018
RTT, Dry eye syndrome, Health, Medicine, Veterinary medicine

The "Global Dry Eye Epidemiology and Patient Flow Analysis - 2018" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Dry Eye Epidemiology and Patient Flow Analysis - 2018" report has been added to ResearchAndMarkets.com's offering.
  • The researcher announced the results of its Dry Eye patients study in a new research Global Dry Eye Epidemiology and Patient Flow Analysis - 2018'.
  • The research provides insights into Dry Eye epidemiology, Dry Eye diagnosed patients, and Dry Eye treatment rate for US, Japan, and EU5 countries.
  • The research provides estimates and forecasts of Dry Eye prevalence, Dry Eye diagnosis rate, and Dry Eye treatment rate for the period 2017 - 2026.

Chinese Dr. Fang Yuan Shares Dry Eye Genome Sequencing Discoveries

Retrieved on: 
Giovedì, Aprile 19, 2018
Biology, Genetic mapping, Genomics, Molecular biology, Genetics, Virus, Genome, Dry eye syndrome, Sequencing

"When this nutrient decreases in the eye's tear film," said Kleyne, "then dry eye disease results."

Key Points: 
  • "When this nutrient decreases in the eye's tear film," said Kleyne, "then dry eye disease results."
  • "Dry eye is like a virus in the eye," Kleyne said.
  • Pursuing that course, Yuan took part in the 10-year Genome Sequencing Project, in which more than 400 countries participated.
  • If you would like to listen to the conversation between Dr. Fang Yuan and Sharon Kleyne, here is the link: https://www.voiceamerica.com/episode/81446/the-sharon-kleyne-hour

Comprehensive Tears & Dry Eye Education Needed Says Water Researcher Sharon Kleyne

Retrieved on: 
Mercoledì, Marzo 28, 2018
Anatomy, RTT, Vision, Medicine, Overuse injuries, Syndromes, Eye, Dry eye syndrome, Sjögren syndrome, Human eye, Tears, Evaporation

Sharon Kleyne Teaches Teaches Tear Layers of the Human Eye & Dry Eye Disease. Sharon Kleyne Seeks More Proactive Global Eye Care Environment.

Key Points: 
  • If you ask people about tears, says Sharon Kleyne, founder of Bio-Logic Aqua Research Water Life Science, "most will probably say that tears are just salty water.
  • Kleyne, one of the most respected body water evaporation and new water research experts in the world, teaches that tears are much more than that.
  • The eyes tear film is naturally 99 percent water, says Kleyne, and when it loses just two percent of its moisture content, a variety of dry eye disease symptoms crop up.
  • Kleyne wants to lead a comprehensive, nationwide education effort, especially in grammar schools, middle schools and high schools, to teach the truth about tears, evaporation, dry eye and a dry eye solution.

China Chooses Nature’s Tears® Eyemist® For Dry Eye Solution®

Retrieved on: 
Mercoledì, Marzo 28, 2018
Dry eye syndrome, RTT, Body fluids, Tears, Anatomy, Veterinary medicine, Vision

China Plagued by Dry Eye Epidemic & Seeks the Perfect Dry Eye Solution®. China & Sharon Kleyne Join Forces To Defeat Dry Eye Disease with Nature’s Tears® EyeMist®.

Key Points: 
  • Kleyne, also a leading expert on dry eye and body water evaporation, has been working to find a solution for Chinas dry eye epidemic for more than two decades.
  • Kleynes work and reputation have made it possible for her to engage with collaborators and partners in China to bring dry eye relief to millions.
  • At the same time, Kleyne reveals, China is embracing Kleynes unique dry eye solution, Natures Tears EyeMist.
  • As users of Natures Tears EyeMist have discovered, millions of Chinese citizens are finding unprecedented dry eye relief with Natures Tears EyeMist.